![]() His classification is still in use in many parts of the world. In 1797, Edward Kentish described the use of pressure dressings to alleviate the effects of burns and blistering, while in 1839, Dupuytren reviewed more than 50 cases of burns and presented a classification with six degrees of burn depth. At the beginning of the 17th century, Guilhelmus Fabricius Hildanus ventured to discuss the pathophysiology of burns, making a unique contribution to the treatment of scar contractures, among other things. In the mid-16th century, Ambrose Paré was one of the first to describe early burn wound excision. The historical writings of Hippocrates, Celsus, and Galen describe increasingly elaborate methods for making ointments, dressings, and treatment regimens for different types of burns. The first formulations for concoctions to be used in burn care can be found already in prehistoric paintings, Egyptian papyri, and ancient Chinese art. Any burn, even relatively minor, can have functional and aesthetic implications lasting throughout the patient’s lifetime.īurns and their treatment have been regarded as an important medical problem since antiquity. The repair process of burn injury, which begins as early as several hours after the traumatic event, may also be impaired by large fluid losses via the wound. The loss of the physical barrier function of the skin opens the door to invasion by harmful microorganisms, which can lead to infection, and ultimately even to the development of sepsis. ![]() These deep structures are a source of proliferating epithelial cells (keratinocytes), which migrate into the clot and wound bed, playing an important role in the wound healing process. It consists of the epidermis and the dermis, deep within which are important skin appendage structures (including hair follicles, sweat glands and sebaceous glands). Skin is the human body’s largest organ, covering a surface area of about 2 sqm in an average adult.
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